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Prospective derivation of a living organoid biobank of colorectal cancer patientsLong-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epitheliumFunctional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumorsA Living Biobank of Breast Cancer Organoids Captures Disease HeterogeneityLong-term expanding human airway organoids for disease modelingExpansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation PotentialThe Organoid Cell AtlasPreserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastasesThe leukemia-associated Mllt10/Af10-Dot1l are Tcf4/beta-catenin coactivators essential for intestinal homeostasisLong-Term Survival of Transplanted Autologous Canine Liver Organoids in a COMMD1-Deficient Dog Model of Metabolic Liver DiseaseSingle Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-γTissue-specific mutation accumulation in human adult stem cells during lifeLong-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic SteatosisLgr6 marks stem cells in the hair follicle that generate all cell lineages of the skinPaneth cells constitute the niche for Lgr5 stem cells in intestinal cryptsUnlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axisRectal Organoids Enable Personalized Treatment of Cystic FibrosisLong-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt SignalsGeneration of L cells in mouse and human small intestine organoidsDifferentiated human colorectal cancer cells protect tumor-initiating cells from irinotecanA living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacologyThe kinase TNIK is an essential activator of Wnt target genes.Organoid models of human and mouse ductal pancreatic cancerIn vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regenerationAn FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistanceStem cells and cancer of the stomach and intestineComparative Proteomics of Colon Cancer Stem Cells and Differentiated Tumor Cells Identifies BIRC6 as a Potential Therapeutic TargetOngoing chromosomal instability and karyotype evolution in human colorectal cancer organoidsLgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomesIdentification of multipotent luminal progenitor cells in human prostate organoid culturesCorrection
author
education
type
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R.G.J. Vries
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Public - No restriction
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Publiek - Geen beperking
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dr.
@en