High-throughput target-selected gene inactivation in zebrafishA zebrafish model for VHL and hypoxia signalingZebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemiaMutations in LRRC50 predispose zebrafish and humans to seminomasHedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafishvon Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafishAsymmetric Hapln1a drives regionalised cardiac ECM expansion and promotes heart morphogenesis in zebrafish developmentHedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential.
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F.J. van Eeden
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Public - No restriction
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Publiek - Geen beperking
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