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Polarized regulatory landscape and Wnt responsiveness underlie Hox activation in embryosX-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific mannerEpigenomic annotation of gene regulatory alterations during evolution of the primate brainReprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cellsTomo-Seq Identifies SOX9 as a Key Regulator of Cardiac Fibrosis During Ischemic InjuryInhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene ExpressionGenome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humansIntracranial Aneurysm-Associated Single-Nucleotide Polymorphisms Alter Regulatory DNA in the Human Circle of WillisAML Subtype Is a Major Determinant of the Association between Prognostic Gene Expression Signatures and Their Clinical SignificanceLarge-scale identification of coregulated enhancer networks in the adult human brainTranscriptomic and Epigenomic Profiling of Histone Deacetylase Inhibitor Treatment Reveals Distinct Gene Regulation Profiles Leading to Impaired Neutrophil DevelopmentMapping the Global Chromatin Connectivity Network for Sox2 Function in Neural Stem Cell MaintenanceTranscriptional Dynamics at Brain EnhancersCdx and T Brachyury Co-activate Growth Signaling in the Embryonic Axial Progenitor NicheLocal compartment changes and regulatory landscape alterations in histone H1-depleted cellsHistone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament networkCircadian networks in human embryonic stem cell-derived cardiomyocytesHominin-specific regulatory elements selectively emerged in oligodendrocytes and are disrupted in autism patientsRecently Evolved Enhancers Emerge with High Interindividual Variability and Less Frequently Associate with Disease
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Menno Creyghton
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Public - No restriction
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Publiek - Geen beperking
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dr.
@en