Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signalingRapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc.ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein responseCyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine.Myc deletion rescues Apc deficiency in the small intestineSpecific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vectorCyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc lossasb11 is a regulator of embryonic and adult regenerative myogenesis
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Public - No restriction
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Publiek - Geen beperking
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drs.
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