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agent
Oral mucosal organoids as a potential platform for personalized cancer therapyDegree and site of chromosomal instability define its oncogenic potentialAttachment issuesEctopic Activation of the Spindle Assembly Checkpoint Signaling Cascade Reveals Its Biochemical DesignMosaic origin of the eukaryotic kinetochoreDesmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathyChromosomal copy number heterogeneity predicts survival rates across cancersNuclear chromosome locations dictate segregation error frequenciesInteractions between N-terminal Modules in MPS1 Enable Spindle Checkpoint SilencingCompromised MPS1 Activity Induces Multipolar Spindle Formation in Oocytes From Aged MaresHuman chromosome-specific aneuploidy is influenced by DNA-dependent centromeric featuresThe molecular basis of monopolin recruitment to the kinetochoreLive imaging of cell division in 3D stem-cell organoid culturesLymphatic Invasion of Plakoglobin-Dependent Tumor Cell Clusters Drives Formation of Polyclonal Lung Metastases in Colon CancerCrystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localizationGermline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposisMolecular characterization of colorectal cancer related peritoneal metastatic diseaseInferring the Evolutionary History of Your Favorite ProteinPermission to passEvolutionary Dynamics of the Spindle Assembly Checkpoint in EukaryotesCyclin B1 scaffolds MAD1 at the kinetochore corona to activate the mitotic checkpointReconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patternsKinetochore-microtubule attachment is sufficient to satisfy the human spindle assembly checkpointChromosomal instability by mutations in the novel minor spliceosome component CENATACUnique Phylogenetic Distributions of the Ska and Dam1 Complexes Support Functional Analogy and Suggest Multiple Parallel Displacements of Ska by Dam1Crowning the KinetochoreChromosome InequalityGenomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protistA Biosensor for the Mitotic Kinase MPS1 Reveals Spatiotemporal Activity Dynamics and RegulationDynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosisPrinciples and dynamics of spindle assembly checkpoint signallingPhylogenomics-guided discovery of a novel conserved cassette of short linear motifs in BubR1 essential for the spindle checkpointKinetochore Malfunction in Human PathologiesIncreased Sampling and Intracomplex Homologies Favor Vertical Over Horizontal Inheritance of the Dam1 ComplexBiallelic TRIP13 mutations predispose to Wilms tumor and chromosome missegregationMicrotubule nucleation from the fibrous corona by LIC1-pericentrin promotes chromosome congressionBCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancerSpindle checkpoint silencing at kinetochores with submaximal microtubule occupancyEvolutionary dynamics of the kinetochore network in eukaryotes as revealed by comparative genomicsLeader of the SAC
author
type
label
Geert Kops
firstName
lastName
name
employeeStartDate
2015-10-01T12:00:00.000+0000
orcid
0000-0003-3555-5295
orcid
workforce_id
staffOrganisationAssociations
visibility
Public - No restriction
@en
Publiek - Geen beperking
@nl