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The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium.Dll1+ secretory progenitor cells revert to stem cells upon crypt damageEphB receptor activity suppresses colorectal cancer progression.Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc.EphB activity suppresses colorectal cancer progressionExpression pattern of Wnt signaling components in the adult intestine.Wnt signaling in the intestinal epithelium: from endoderm to cancer.SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus productionCanonical Wnt signals are essential for homeostasis of the intestinal epitheliumIn situ hybridization to identify gut stem cellsWnt signalling induces maturation of Paneth cells in intestinal crypts.Hindgut defects and transformation of the gastro-intestinal tract in Tcf4-/-/Tcf1-/- embryos
author
education
type
label
A. Gregorieff
firstName
lastName
Gregorieff
name
employeeId
staffOrganisationAssociations
visibility
Public - No restriction
@en
Publiek - Geen beperking
@nl
relatedLink
title
drs.
@en