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COmplement factor 3a alters proteasome function in human RPE cells and in animal model of age-related RPE degeneration.Abcc6 deficiency in the mouse leads to calcification of collagen fibers in Bruch's membrane.Alzheimer's disease and glaucoma-replyDietary magnesium, not calcium, prevents vascular calcification in a mouse model for pseudoxanthoma elasticum.Abcc6 deficiency causes increased infarct size and apoptosis in a mouse cardiac ischemia-reperfusion model.The level of hepatic ABCC6 expression determines the severity of calcification after cardiac injuryMapping mRNA Expression of Glaucoma Genes in the Healthy Mouse EyeGene expression and functional annotation of the human and mouse choroid plexus epithelium.Increased High-Density Lipoprotein Levels Associated with Age-Related Macular DegenerationThe complement component 5 gene and age-related macular degeneration.Modelling the Mechanical Parameters of GlaucomaPseudoxanthoma Elasticum: cardiac findings in patients and Abcc6-deficient mouse model.Genome-wide meta-analyses of multi-ethnic cohorts identify multiple new susceptibility loci for refractive error and myopia.A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum.Stem Cell Derived Retinal Pigment EpitheliumPlasmalemma Vesicle-Associated Protein Has a Key Role in Blood-Retinal Barrier LossComparison of Mouse and Human Retinal Pigment Epithelium Gene Expression ProfilesGene expression-based comparison of the human secretory neuroepithelia of the brain choroid plexus and the ocular ciliary bodyGene expression and functional annotation of the human ciliary body epithelia.The European Eye Epidemiology spectral-domain optical coherence tomography classification of macular diseases for epidemiological studiesMulticenter cohort association study of SLC2A1 single nucleotide polymorphisms and age-related macular degeneration.The ERCC6 gene and age-related macular degeneration.Comprehensive bioinformatics analysis of trabecular meshwork gene expression data to unravel the molecular pathogenesis of primary open-angle glaucomaThe action spectrum of photochemical damage to the retina: a review of monochromatic threshold data.In silico analysis of the molecular machinery underlying aqueous humor production: potential implications for glaucoma.The vast complexity of primary open angle glaucoma: disease genes, risks, molecular mechanisms and pathobiology.The dynamic nature of Bruch's membrane.Abcc6 deficiency in mice leads to altered ABC transporter gene expression in metabolic active tissuesDisseminated arterial calcification and enhanced myogenic response are associated with abcc6 deficiency in a mouse model of pseudoxanthoma elasticumFunctional annotation of the human retinal pigment epithelium transcriptome.ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release.Genetic deletion of Abcc6 disturbs cholesterol homeostasis in miceGene expression and functional annotation of human choroid plexus epithelium failure in Alzheimer's disease
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T.G.M.F. Gorgels
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Public - No restriction
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Publiek - Geen beperking
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dr.
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