993978bc-a2ae-46e9-a21a-34d6a06cc8a5
Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancerGenomic DNA pooling strategy for next-generation sequencing-based rare variant discovery in abdominal aortic aneurysm regions of interest-challenges and limitationsGenomic and Functional Overlap between Somatic and Germline Chromosomal RearrangementsCloning and expression of new microRNAs from zebrafishChromothripsis as a mechanism driving complex de novo structural rearrangements in the germlineMulti-contact 4CPatient-Derived Ovarian Cancer Organoids Mimic Clinical Response and Exhibit Heterogeneous Inter- and Intrapatient Drug ResponsesThe diverse functions of microRNAs in animal development and disease.An organoid platform for ovarian cancer captures intra- and interpatient heterogeneityGenomic and transcriptomic plasticity in treatment-naive ovarian cancerReconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patternsChromothripsis in congenital disorders and cancer: similarities and differencesEnhancer hubs and loop collisions identified from single-allele topologiesChromothripsis in healthy individuals affects multiple protein-coding genes and can result in severe congenital abnormalities in offspringDifferences in vertebrate microRNA expressionMEFV mutations affecting pyrin amino acid 577 cause autosomal dominant autoinflammatory diseaseDiscovery of variants unmasked by hemizygous deletionsMultiplexed array-based and in-solution genomic enrichment for flexible and cost-effective targeted next-generation sequencingMouse microRNA profiles determined with a new and sensitive cloning methodConstitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanismsMate pair sequencing for the detection of chromosomal aberrations in patients with intellectual disability and congenital malformationsDominant missense mutations in ABCC9 cause Cantu syndromeImproving mammalian genome scaffolding using large insert mate-pair next-generation sequencing