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
agent
Sequence-specific high mobility group box factors recognize 10-12-base pair minor groove motifsBeta- catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinBThe human Tcf-1 gene encodes a nuclear DNA-binding protein, uniquely expressed in normal and neoplastic T lineage lymphocytesCloning of the murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and TCR-alpha enhancersThe murine Sox-4 protein is encoded on a single exonHMG box proteins in early T cell differentiationWnt activates the Tak1/Nlk kinase pathwayThe inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus.Extensive alternative splicing and dual promoter usage generates TCF-1 protein isoforms with differential transcription control propertiesAn HMG box containing T-cell factor required for thymocyte differentiationSox-4 gene is required for cardiac outflow tract formation and pro-B lymphocyte expansionSOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genesGenomic organization of the segment polarity gene pan in Drosophila melanogasterEctopic Wnt signal determines the eyeless phenotype of zebrafish masterblind mutantThe Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressorsMutant E-cadherin breast cancer cells do not display constitutive Wnt signalingDifferential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesisSOX-4, an SRY-like HMG box protein, is a transcriptional activator in lymphocytesWnt signaling regulates expression of the receptor tyrosine kinase met in colorectal cancerThe Intestinal Wnt/TCF SignatureBeta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formationTcf-1-mediated transcription in T lymphocytes: differential role for GSK3beta in fibroblasts and T cellsClonal acquisition of the Ly49A NK cell receptor is dependent on the trans-acting factor TCF-1Armadillo co-activates transcription driven by the product of the Drosophila segment polarity gene dTCFSequence-specific interaction of the HMG-box factor TCF-1 occurs within the minor groove of a Watson-Crick double helixTCF/LEF factors earn their wingsIdentification of APC2, a homologue of the adenomatous polyposis coli tumour suppressorStructure and mapping of the human TCF-1 gene; Characterization of its promoterXtcf-3 Transcription factor mediates beta-catenin-induced axis formation in xenopus embryosAberrant Polycystin-1 Expression Results in Modification of Activator Protein-1 Activity, whereas Wnt Signaling Remains UnaffectedSpecific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vectorNegative feedback loop of Wnt ignaling through upregulation of conductin/axin2 in colorectal and liver tumorsWNT signaling and lymphocyte developmentThe beta catenin/TCF4 complex imposes a crypt progenitor phenotype on colorectal cancer cellsAll Tcf HMG box transcription factors interact with Groucho-related co-repressorsSolution structure of the sequence-specific HMG box of the lymphocyte transcriptional activator SOX-4Identification and cloning of TCF-1, a T cell-specific transcription factor containing a sequence-specific HMG boxIdentification of two novel regulated serines in the N terminus of beta-cateninSox 15, a novel member of the murine Sox family of HMG box transcription factorsThe Schizosaccharomyces pombe mating-type gene mat-MC encodes a sequence-specific DNA-binding HMG box protein
author
type
label
M. van de Wetering