d90ec0a6-32db-4004-8224-5b4cadfe76d2
Establishment of human fetal hepatocyte organoids and CRISPR-Cas9-based gene knockin and knockout in organoid cultures from human liverDegree and site of chromosomal instability define its oncogenic potentialFunctional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumorsSARS-CoV-2 infection and replication in human gastric organoidsTroy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornificationA path to translationChromosomal copy number heterogeneity predicts survival rates across cancersmRNA structural dynamics shape Argonaute-target interactionsNuclear chromosome locations dictate segregation error frequenciesCompromised MPS1 Activity Induces Multipolar Spindle Formation in Oocytes From Aged MaresPatient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancerOrganoids and organs-on-chipsEpigenetic and Transcriptional Networks Underlying Atrial FibrillationAdvancing lung organoids for COVID-19 researchIn vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bedMultistep mechanism of G-quadruplex resolution during DNA replicationRole of the cellular factor CTCF in the regulation of bovine leukemia virus latency and three-dimensional chromatin organizationMathematical model of colorectal cancer initiationA turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calciumSingle-cell Ribo-seq reveals cell cycle-dependent translational pausingAdult mouse and human organoids derived from thyroid follicular cells and modeling of Graves' hyperthyroidismH3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrityIlluminating RNA trafficking and functional delivery by extracellular vesiclesThe Organoid Cell AtlasSister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51A bipotential organoid model of respiratory epithelium recapitulates high infectivity of SARS-CoV-2 Omicron variantThe H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric gliomaA public-private partnership model for COVID-19 diagnosticsA CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronavirusesHeterogeneity in mRNA TranslationGenetic Dissection of a Super Enhancer Controlling the Nppa-Nppb Cluster in the HeartNational Heart, Lung, and Blood Institute and Building Respiratory Epithelium and Tissue for Health (BREATH) Consortium Workshop ReportEpigenetic Analyses of Human Left Atrial Tissue Identifies Gene Networks Underlying Atrial FibrillationHost phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathologyColon Tumors in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized Mice Do Not Display a Unique Mutational Signature but Instead Possess Host-Dependent Alterations in the APC GeneAnalysis of the glyco-code in pancreatic ductal adenocarcinoma identifies glycan-mediated immune regulatory circuitsPrimary Intestinal Epithelial Organoid CultureLifeTime and improving European healthcare through cell-based interceptive medicinePatient-derived micro-organospheres enable clinical precision oncologyLoss of Rnf43 accelerates Kras-mediated neoplasia and remodels the tumor immune microenvironment in pancreatic adenocarcinoma
externalOrganisations
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