b47e96de-fbb0-4183-b20a-b30bbcefa16b
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumorsSARS-CoV-2 infection and replication in human gastric organoidsDesmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathyCell Type Purification by Single-Cell Transcriptome-Trained SortingPatient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancerSpatial transcriptomics unveils ZBTB11 as a regulator of cardiomyocyte degeneration in arrhythmogenic cardiomyopathyModeling breast cancer using CRISPR/Cas9-mediated engineering of human breast organoidsIntestinal RegenerationGene editing innovations and their applications in cardiomyopathy researchCombinatorial single-cell profiling of major chromatin types with MAbIDA dualistic approach to heart repair through FGF10Nanoblades allow high-level genome editing in murine and human organoidsPatient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenovirusesA pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progressionHigh-Resolution mRNA and Secretome Atlas of Human Enteroendocrine CellsSex Differences in ScienceSingle-cell transcriptomics provides insights into hypertrophic cardiomyopathyMapping prohormone processing by proteases in human enteroendocrine cells using genetically engineered organoid modelsSingle-cell profiling of transcriptome and histone modifications with EpiDamIDEstablishment of patient-derived cancer organoids for drug-screening applicationsPITX2 induction leads to impaired cardiomyocyte function in arrhythmogenic cardiomyopathyConformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoidsOxidative Stress Leads to β-Cell Dysfunction Through Loss of β-Cell IdentityEstablishment and Culture of Human Intestinal Organoids Derived from Adult Stem CellsEvaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoidsThymosin β4 and prothymosin α promote cardiac regeneration post-ischaemic injury in miceSnake Venom Gland OrganoidsAssessing the origin of high-grade serous ovarian cancer using CRISPR-modification of mouse organoidsCRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid BiobankMacrophages provide a transient muscle stem cell niche via NAMPT secretionDevelopment in a Dish-In Vitro Models of Mammalian Embryonic DevelopmentEndothelial struts enable the generation of large lumenized blood vessels de novoOne-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoidsThe Organoid PlatformCardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturationRapid tissue prototyping with micro-organospheresEnteroendocrine Dynamics - New Tools Reveal Hormonal Plasticity in the GutThe frontier of live tissue imaging across space and timeHigh-resolution 3D imaging of fixed and cleared organoidsThe role of heterochromatin in 3D genome organization during preimplantation development
externalOrganisations
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