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Unraveling the ubiquitin-regulated signaling networks by mass spectrometry-based proteomicsCoupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stressThe Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markersPlasma membrane proteomics of human embryonic stem cells and human embryonal carcinoma cells.Phosphorylation dynamics during early differentiation of human embryonic stem cellsControl of Epithelial Cell Migration and Invasion by the IKKbeta- and CK1alpha-Mediated Degradation of RAPGEF2Quantitative and qualitative proteome characteristics extracted from in-depth integrated genomics and proteomics analysisThe kinase TNIK is an essential activator of Wnt target genes.The time is right: proteome biology of stem cells.In depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immuno-affinity purification and stable isotope dimethyl labelingTumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptorsWnt signaling through inhibition of beta-catenin degradation in an intact Axin1 complexProteome biology of stem cells: a new joint HUPO and ISSCR initiative.
author
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A.J.R. Heck