a842451b-b9d4-4f70-ac4a-1c8c31da8afe
Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancerRecurrent de novo missense variants across multiple histone H4 genes underlie a neurodevelopmental syndromeNuclear chromosome locations dictate segregation error frequenciesA pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progressionSingle-cell profiling of transcriptome and histone modifications with EpiDamID