Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivoFrizzled7 functions as a wnt receptor in intestinal epithelial lgr5(+) stem cellsFrizzled-7 is required for Wnt signaling in gastric tumors with and without Apc mutationsInactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinomaIdentification of stem cells in small intestine and colon by marker gene Lgr5LGR5 positivity defines stem-like cells in colorectal cancerLeucine-rich repeat-containing G-protein-coupled Receptor 5 marks short-term hematopoietic stem and progenitor cells during mouse embryonic developmentOvarian LGR5 is critical for successful pregnancy
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Nick Barker