Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germlineRecombinant vitronectin is a functionally defined substrate that supports human embryonic stem cell self-renewal via alphavbeta5 integrin.Improved genetic manipulation of human embryonic stem cells.Discovery of variants unmasked by hemizygous deletionsConstitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanisms
author
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R. Hochstenbach
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Hochstenbach