Reduced amyloid beta degradation in early Alzheimer's diesease but not in the APPswePS1dE9 and 3xTg-AD mouse modles.COmplement factor 3a alters proteasome function in human RPE cells and in animal model of age-related RPE degeneration.polyglutamine expansion accelerates the dynamics of ataxin-1 and does not result in aggregate formation.
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E.A. Reits