Targeted ablation of Crb1 and Crb2 in retinal progenitor cells mimics Leber Congenital Amaurosis.Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background.Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.PALS1 is essential for retinal pigment epithelium structure and neural retina stratification.
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C.H. Alves