A transgenic mouse model for "lipid hang-up", or why pathologists need to be involved in genetically engineered mouse modellingTranscription factor achaete scute-like 2 controls intestinal stem cell fate.Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.
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M.E. van Gijn