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Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stressThe Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markersControl of Epithelial Cell Migration and Invasion by the IKKbeta- and CK1alpha-Mediated Degradation of RAPGEF2The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/beta-catenin coactivators essential for intestinal homeostasisLgr5 homologues associate with Wnt receptors and mediate R-spondin signallingMAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathwayComparative phosphoproteomics of zebrafish Fyn/Yes morpholino knockdown embryos.Quantitative and qualitative proteome characteristics extracted from in-depth integrated genomics and proteomics analysisThe kinase TNIK is an essential activator of Wnt target genes.Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptorsHighly sensitive proteome analysis of FACS-sorted adult colon stem cellsOnline automated in vivo zebrafish phosphoproteomics: from large-scale analysis down to a single embryo.Wnt signaling through inhibition of beta-catenin degradation in an intact Axin1 complex
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S. Mohammed