Targeted ablation of Crb1 and Crb2 in retinal progenitor cells mimics Leber Congenital Amaurosis.Research models and gene augmentation therapy for CRB1 retinal dystrophies.Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.GFAP-driven GFP expression in activated mouse Muller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors.
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L.P. Pellissier
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Pellissier