2273c114-db00-433a-af7e-ce1eeb06f3e1
Recurrent de novo missense variants across multiple histone H4 genes underlie a neurodevelopmental syndromeEstablishment of human fetal hepatocyte organoids and CRISPR-Cas9-based gene knockin and knockout in organoid cultures from human liverCommon Genetic Variants Contribute to Risk of Transposition of the Great ArteriesG-quadruplex resolutionReport of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug DevelopmentPerspectives on automated composition of workflows in the life sciencesOxidative stress in pancreatic alpha and beta cells as a selection criterion for biocompatible biomaterialsSister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51β-Cell Stress Shapes CTL Immune Recognition of Preproinsulin Signal Peptide by Posttranscriptional Regulation of Endoplasmic Reticulum Aminopeptidase 1A public-private partnership model for COVID-19 diagnosticsEpicardial differentiation drives fibro-fatty remodeling in arrhythmogenic cardiomyopathySpatial transcriptomics reveals asymmetric cellular responses to injury in the regenerating spiny mouse (Acomys) earContact lens-related fungal keratitisAnalysis of the glyco-code in pancreatic ductal adenocarcinoma identifies glycan-mediated immune regulatory circuitsStrand-specific single-cell methylomics reveals distinct modes of DNA demethylation dynamics during early mammalian developmentSafety and feasibility of intradermal injection with tolerogenic dendritic cells pulsed with proinsulin peptide-for type 1 diabetesCercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafishCardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent mannerBRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombinationEngineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosisOrganoid models of fibrolamellar carcinoma mutations reveal hepatocyte transdifferentiation through cooperative BAP1 and PRKAR2A lossFunctional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancerEvidence generation and reproducibility in cell and gene therapy researchOxidative Stress Leads to β-Cell Dysfunction Through Loss of β-Cell IdentityDisease modeling following organoid-based expansion of airway epithelial cellsBuilding consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoidsThe zebrafish grime mutant uncovers an evolutionarily conserved role for Tmem161b in the control of cardiac rhythmChaperoning of the histone octamer by the acidic domain of DNA repair factor APLFDevelopment of Plasmodium falciparum liver-stages in hepatocytes derived from human fetal liver organoid culturesOne-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoidsFamilies in comparison: An individual-level comparison of life-course and family reconstructions between population and vital event registersSingle-Cell Transcriptomics Links Loss of Human Pancreatic β-Cell Identity to ER StressInterplay between calcium and sarcomeres directs cardiomyocyte maturation during regenerationRobust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencingFast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editingCAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strandsAn organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneityFormalin-Fixed, Paraffin-Embedded-Targeted Locus CaptureA High Cell-Bearing Capacity Multibore Hollow Fiber Device for Macroencapsulation of Islets of LangerhansThe EHA Research Roadmap
externalOrganisations
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