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Microglia, circadian rhythm and lifestyle factorsHypothalamic neuropeptides and neurocircuitries in Prader Willi syndromeMicroglia-specific knock-down of Bmal1 improves memory and protects mice from high fat diet-induced obesityThe Effect of Rev-erbα Agonist SR9011 on the Immune Response and Cell Metabolism of MicrogliaHormonal control of metabolism by the hypothalamus-autonomic nervous system-liver axisLoss of Microglial Insulin Receptor Leads to Sex-Dependent Metabolic Disorders in Obese MiceLoss of arginine vasopressin- and vasoactive intestinal polypeptide-containing neurons and glial cells in the suprachiasmatic nucleus of individuals with type 2 diabetesReduction of oxytocin-containing neurons and enhanced glymphatic activity in the hypothalamic paraventricular nucleus of patients with type 2 diabetes mellitusLipoprotein Lipase Maintains Microglial Innate Immunity in ObesityTime-restricted feeding during the inactive phase abolishes the daily rhythm in mitochondrial respiration in rat skeletal muscleDeficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase.Time-Restricted Feeding Improves Glucose Tolerance in Rats, but Only When in Line With the Circadian Timing SystemDiet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day MannerThe Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1Lipid Droplets accumulate in the hypothalamus of mice and humans with and without metabolic diseasesDeficiency of the Circadian Clock Gene Bmal1 Reduces Microglial ImmunometabolismMapping of microglial brain region, sex and age heterogeneity in obesityThe impact of antidiabetic treatment on human hypothalamic infundibular neurons and microgliaSpecific Silencing of Microglial Gene Expression in the Rat Brain by Nanoparticle-Based Small Interfering RNA DeliveryDietary sugars, not lipids, drive hypothalamic inflammationMicroglial phagolysosome dysfunction and altered neural communication amplify phenotypic severity in Prader-Willi Syndrome with larger deletion
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Chun-Xia Yi