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Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancerLRRC50, a conserved ciliary protein implicated in polycystic kidney disease.Limitations and possibilities of small RNA digital gene expression profilingA zebrafish model for VHL and hypoxia signalingInterplay between VHL/HIF1alpha and Wnt/beta-catenin pathways during colorectal tumorigenesis.Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemiaMutations in LRRC50 predispose zebrafish and humans to seminomasPrimary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatmentvon Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafishEthical, legal, and counseling challenges surrounding the return of genetic results in oncology
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E.E. Voest