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Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screeningIdentification of the stress granule transcriptome via RNA-editing in single cells and in vivoDrug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancerChromosomal copy number heterogeneity predicts survival rates across cancersDifferential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell MicroenvironmentsHherisomes, Hedgehog specialized recycling endosomes, are required for high level Hedgehog signaling and tissue growthReconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patternsElevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemiaActivation of IRE1, PERK and salt-inducible kinases leads to Sec body formation in Drosophila S2 cellsStress-induced phase separation of ERES components into Sec bodies precedes ER exit inhibition in mammalian cells
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