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Caught up in a Wnt storm: Wnt signaling in cancerMutations in the APC tumor suppressor gene cause chromosomal instability in colorectal cancerLRRC50, a conserved ciliary protein implicated in polycystic kidney disease.A zebrafish model for VHL and hypoxia signalingThe many faces of the tumor suppressor gene APCThe serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafishInterplay between VHL/HIF1alpha and Wnt/beta-catenin pathways during colorectal tumorigenesis.Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemiaMutations in LRRC50 predispose zebrafish and humans to seminomasvon Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish
author
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R.H. Giles