Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans.Zebrafish prox1b Mutants Develop a Lymphatic Vasculature, and prox1b Does Not Specifically Mark Lymphatic Endothelial CellsCcbe1 is required for embryonic lymphangiogenesis and venous sproutingVegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries.
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M. de Witte